[Calcium pros and cons: long term use of bisphosphonates. Bisphosphonates should be used for postmenopausal osteoporosis for a long term]

Abstract

Only bisphosphonates have evidence that show to reduce the risk of vertebral, nonvertebral, and hip fractures in postmenopausal osteoporosis. From the viewpoint of risk benefit, it may be said that a utility is far superior to problems of the long-term use. Long-term use of bisphosphonates is necessary for the patients at elevated risk for the hip fracture.