Genomics reaches the clinic: from basic discoveries to clinical impact
- PMID: 21962499
- DOI: 10.1016/j.cell.2011.09.012
Genomics reaches the clinic: from basic discoveries to clinical impact
Abstract
Today, more than ever, basic science research provides significant opportunities to advance our understanding about the genetic basis of human disease. Close interactions among laboratory, computational, and clinical research communities will be crucial to ensure that genomic discoveries advance medical science and, ultimately, improve human health.
Copyright © 2011 Elsevier Inc. All rights reserved.
Similar articles
-
Review article: genetic susceptibility and application of genetic testing in clinical management of inflammatory bowel disease.Aliment Pharmacol Ther. 2006 Oct;24 Suppl 3:2-10. doi: 10.1111/j.1365-2036.2006.03052.x. Aliment Pharmacol Ther. 2006. PMID: 16961737 Review.
-
Clinical aspects of inflammatory bowel disease.Eur J Immunol. 2009 Aug;39(8):2026-30. doi: 10.1002/eji.200939601. Eur J Immunol. 2009. PMID: 19672897
-
Genome-based prediction of common diseases: advances and prospects.Hum Mol Genet. 2008 Oct 15;17(R2):R166-73. doi: 10.1093/hmg/ddn250. Hum Mol Genet. 2008. PMID: 18852206 Review.
-
Translating genomic biomarkers into clinically useful diagnostics.Expert Rev Mol Diagn. 2006 Mar;6(2):179-91. doi: 10.1586/14737159.6.2.179. Expert Rev Mol Diagn. 2006. PMID: 16512778 Review.
-
Genomics shifts focus to rare diseases.Nature. 2009 Sep 24;461(7263):458. doi: 10.1038/461458a. Nature. 2009. PMID: 19779424 No abstract available.
Cited by
-
Pharmacogenomics discovery and implementation in genome-wide association studies era.Wiley Interdiscip Rev Syst Biol Med. 2013 Jan-Feb;5(1):1-9. doi: 10.1002/wsbm.1199. Epub 2012 Nov 27. Wiley Interdiscip Rev Syst Biol Med. 2013. PMID: 23188748 Free PMC article. Review.
-
Resolving the variable genome and epigenome in human disease.J Intern Med. 2012 Apr;271(4):379-91. doi: 10.1111/j.1365-2796.2011.02508.x. J Intern Med. 2012. PMID: 22443201 Free PMC article. Review.
-
A population approach to precision medicine.Am J Prev Med. 2012 Jun;42(6):639-45. doi: 10.1016/j.amepre.2012.02.012. Am J Prev Med. 2012. PMID: 22608383 Free PMC article.
-
Prioritizing genomic applications for action by level of evidence: a horizon-scanning method.Clin Pharmacol Ther. 2014 Apr;95(4):394-402. doi: 10.1038/clpt.2013.226. Epub 2014 Feb 19. Clin Pharmacol Ther. 2014. PMID: 24398597 Free PMC article. Review.
-
The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future.Genet Med. 2013 Oct;15(10):761-71. doi: 10.1038/gim.2013.72. Epub 2013 Jun 6. Genet Med. 2013. PMID: 23743551 Free PMC article. Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Research Materials
Miscellaneous