Editorial: granulopoiesis versus monopoiesis: a consequence of transcription factors dancing with the right partners
- PMID: 21965310
- PMCID: PMC3177698
- DOI: 10.1189/jlb.0411187
Editorial: granulopoiesis versus monopoiesis: a consequence of transcription factors dancing with the right partners
Abstract
Discussion on the intricate regulation of C/EBPA transcriptional activity and the delicate balance between normal myelopoiesis and transformation to AML.
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Comment on
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AP-1 protein induction during monopoiesis favors C/EBP: AP-1 heterodimers over C/EBP homodimerization and stimulates FosB transcription.J Leukoc Biol. 2011 Oct;90(4):643-51. doi: 10.1189/jlb.0111043. Epub 2011 May 4. J Leukoc Biol. 2011. PMID: 21543584 Free PMC article.
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References
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- Reckzeh K., Cammenga J. (2010) Molecular mechanisms underlying deregulation of C/EBPα in acute myeloid leukemia. Int. J. Hematol. 91, 557–568 - PubMed
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- Friedman A. D., McKnight S. L. (1990) Identification of two polypeptide segments of CCAAT/enhancer-binding protein required for transcriptional activation of the serum albumin gene. Genes Dev. 4, 1416–1426 - PubMed
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