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. 2011 Oct:52 Suppl 8:28-30.
doi: 10.1111/j.1528-1167.2011.03230.x.

Febrile infection-related epilepsy syndrome (FIRES): does duration of anesthesia affect outcome?

Uri Kramer  1 , Ching-Shiang Chi, Kuang-Lin Lin, Nicola Specchio, Mustafa Sahin, Heather Olson, Gerhard Kluger, Andreas van Baalen
Affiliations

Febrile infection-related epilepsy syndrome (FIRES): does duration of anesthesia affect outcome?

Uri Kramer et al. Epilepsia. 2011 Oct.

Abstract

We conducted a retrospective multicenter study on children who had been included in eight studies published between November 2001 and July 2010 to explore the correlations between burst-suppression coma (BSC) with outcome in febrile infection-related epilepsy syndrome (FIRES). The 77 enrolled patients presented with prolonged refractory status epilepticus. BSC was induced in 46 patients. Cognitive levels at follow-up were significantly associated with duration of a BSC (p=0.005). The outcome of FIRES is poor. Treatment by inducing a prolonged BSC was associated with a worse cognitive outcome.

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