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. 2010 Nov;72(6):689-96.
doi: 10.4103/0250-474X.84576.

Polymers for colon targeted drug delivery

H Rajpurohit  1 , P Sharma, S Sharma, A Bhandari
Affiliations

Polymers for colon targeted drug delivery

H Rajpurohit et al. Indian J Pharm Sci. 2010 Nov.

Abstract

The colon targeted drug delivery has a number of important implications in the field of pharmacotherapy. Oral colon targeted drug delivery systems have recently gained importance for delivering a variety of therapeutic agents for both local and systemic administration. Targeting of drugs to the colon via oral administration protect the drug from degradation or release in the stomach and small intestine. It also ensures abrupt or controlled release of the drug in the proximal colon. Various drug delivery systems have been designed that deliver the drug quantitatively to the colon and then trigger the release of drug. This review will cover different types of polymers which can be used in formulation of colon targeted drug delivery systems.

Keywords: Biodegradable polymers; colon targeted delivery; controlled delivery; polysaccharides.

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Figures

Fig. 1
Fig. 1
Structure of Guar Gum
Fig. 2
Fig. 2
Structure of Pectin
Fig. 3
Fig. 3
Structure of chondroitin sulfate
Fig. 4
Fig. 4
Structure of dextran
Fig. 5
Fig. 5
Structure of chitosan
Fig. 6
Fig. 6
Structure of α-cyclodextrin
Fig. 7
Fig. 7
Structure of inulin
Fig. 8
Fig. 8
Structure of amylose
See this image and copyright information in PMC

References

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