Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2011;15(5):311.
doi: 10.1186/cc10470. Epub 2011 Sep 30.

Neuromuscular blockers and ARDS: thou shalt not breathe, move, or die!

Affiliations
Comment

Neuromuscular blockers and ARDS: thou shalt not breathe, move, or die!

Balaji Yegneswaran et al. Crit Care. 2011.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Forest plot of trials comparing cisatracurium with placebo for 28-day mortality in severe ARDS. Data from studies demonstrate the relative risk (RR) with 95% confidence intervals (CI) for mortality with cisatracurium vs. placebo in patients with ARDS. The RRs < 1 suggest reduced mortality with cisatracurium compared to placebo, whereas RRs >1 suggest increased mortality with cisatracurium. The size of the data markers corresponds to the weight of the studies. Larger markers imply less uncertainty from the results of the individual study and carry more weight in calculating the fixed effects pooled estimate from the systematic review.

Comment on

  • Neuromuscular blockers in early acute respiratory distress syndrome.
    Papazian L, Forel JM, Gacouin A, Penot-Ragon C, Perrin G, Loundou A, Jaber S, Arnal JM, Perez D, Seghboyan JM, Constantin JM, Courant P, Lefrant JY, Guérin C, Prat G, Morange S, Roch A; ACURASYS Study Investigators. Papazian L, et al. N Engl J Med. 2010 Sep 16;363(12):1107-16. doi: 10.1056/NEJMoa1005372. N Engl J Med. 2010. PMID: 20843245 Clinical Trial.

References

Article details

    1. Sachin Yende, editor. University of Pittsburgh Department of Critical Care Medicine: Evidence-Based Medicine Journal Club.

References

    1. Frutos-Vivar F, Nin N, Esteban A. Epidemiology of acute lung injury and acute respiratory distress syndrome. Curr Opin Crit Care. 2004;10:1–6. - PubMed
    1. Luhr OR, Antonsen K, Karlsson M. et al.Incidence and mortality after acute respiratory failure and acute respiratory distress syndrome in Sweden, Denmark, and Iceland. The ARF Study Group. Am J Respir Crit Care Med. 1999;159:1849–1861. - PubMed
    1. Rubenfeld GD, Caldwell E, Peabody E. et al.Incidence and outcomes of acute lung injury. N Engl J Med. 2005;353:1685–1693. doi: 10.1056/NEJMoa050333. - DOI - PubMed
    1. Esan A, Hess DR, Raoof S, George L, Sessler CN. Severe hypoxemic respiratory failure: part 1 - ventilatory strategies. Chest. 2010;137:1203–1216. doi: 10.1378/chest.09-2415. - DOI - PubMed
    1. Raoof S, Goulet K, Esan A, Hess DR, Sessler CN. Severe hypoxemic respiratory failure: part 2 - nonventilatory strategies. Chest. 2010;137:1437–1448. doi: 10.1378/chest.09-2416. - DOI - PubMed

LinkOut - more resources