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Randomized Controlled Trial
. 2011 Dec;34(12):2502-7.
doi: 10.2337/dc11-1150. Epub 2011 Oct 4.

The LiP (Lifestyle in Pregnancy) study: a randomized controlled trial of lifestyle intervention in 360 obese pregnant women

Christina A Vinter  1 , Dorte M Jensen, Per Ovesen, Henning Beck-Nielsen, Jan S Jørgensen
Affiliations
Randomized Controlled Trial

The LiP (Lifestyle in Pregnancy) study: a randomized controlled trial of lifestyle intervention in 360 obese pregnant women

Christina A Vinter et al. Diabetes Care. 2011 Dec.

Abstract

Objective: To study the effects of lifestyle intervention on gestational weight gain (GWG) and obstetric outcomes.

Research design and methods: The LiP (Lifestyle in Pregnancy) study was a randomized controlled trial in 360 obese women allocated in early pregnancy to lifestyle intervention or control. The intervention program included dietary guidance, free membership in fitness centers, physical training, and personal coaching.

Results: A total of 360 obese pregnant women were included, and 304 (84%) were followed up until delivery. The intervention group had a significantly lower median (range) GWG compared with the control group of 7.0 (4.7-10.6) vs. 8.6 kg (5.7-11.5; P = 0.01). The Institute of Medicine (IOM) recommendations on GWG were exceeded in 35.4% of women in the intervention group compared with 46.6% in the control group (P = 0.058). Overall, the obstetric outcomes between the two groups were not significantly different.

Conclusions: Lifestyle intervention in pregnancy resulted in limited GWG in obese pregnant women. Overall obstetric outcomes were similar in the two groups. Lifestyle intervention resulted in a higher adherence to the IOM weight gain recommendations; however, a significant number of women still exceeded the upper threshold.

Trial registration: ClinicalTrials.gov NCT00530439.

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Figures

Figure 1
Figure 1
Flowchart shows selection and participation in the LiP study. OGTT, oral glucose tolerance test.
See this image and copyright information in PMC

Comment in

References

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