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. 2011 Aug;35(4):374-83.
doi: 10.4093/dmj.2011.35.4.374. Epub 2011 Aug 31.

The Correlations between Extremity Circumferences with Total and Regional Amounts of Skeletal Muscle and Muscle Strength in Obese Women with Type 2 Diabetes

Hwi Ryun Kwon  1 , Kyung Ah Han, Hee Jung Ahn, Jae Hyuk Lee, Gang Seo Park, Kyung Wan Min
Affiliations

The Correlations between Extremity Circumferences with Total and Regional Amounts of Skeletal Muscle and Muscle Strength in Obese Women with Type 2 Diabetes

Hwi Ryun Kwon et al. Diabetes Metab J. 2011 Aug.

Abstract

Background: Insulin resistance is related to central obesity and the amount of skeletal muscle. A simple and practical anthropometric marker for muscle mass is not known, although waist circumference (WC) is used as an indicator of abdominal obesity. The aims of this study were to investigate whether arm (AC) and thigh circumferences (TC) can be used as an indicator of muscle mass and if they are related to muscle strength.

Methods: A total of 110 obese (body mass index [BMI]≥25 kg/m(2)) women with type 2 diabetes were enrolled, and WC, AC, and TC were measured. Abdominal visceral fat (AVF), subcutaneous fat (ASF), and total fat (ATF) were assessed by computed tomography, regional muscle (MM), and fat mass by dual-energy X-ray absorptiometry, muscle strength by one repetition maximum (1RM) of both extremities (chest and leg press) and insulin resistance by K(ITT).

Results: The mean age was 56.2±7.3 years, duration of diabetes was 4.2±4.4 years, and BMI was 27.2±2.8 kg/m(2). WC was correlated with ATF, AVF, and ASF (r=0.728, P<0.001; r=0.515, P<0.001; r=0.608, P<0.001, respectively). Arm MM was correlated with AC (r=0.500, P<0.001), and leg MM with TC (r=0.291, P=0.002). Upper 1RM was related to AC/WC ratio (r=0.359, P<0.001), and lower 1RM was to TC/WC ratio (r=0.286, P=0.003). Insulin resistance had significant relations with AVF, WC, and total MM (r=-0.262, P=0.008; r=-0.217, P=0.029; r=0.160, P=0.031, respectively).

Conclusion: The muscle mass was related to extremity circumferences, and muscle strength was to extremity/waist circumference ratio in obese women with type 2 diabetes.

Keywords: Circumference; Diabetes mellitus, type 2; Muscle mass; Muscle strength.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
Correlations between muscle mass, circumference and arm/waist circumference ratio.
Fig. 2
Fig. 2
Correlations between muscle strength, circumference and arm/waist circumference ratio. 1RM, one repetition maximum.
See this image and copyright information in PMC

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References

    1. McKeigue PM, Marmot MG, Adelstein AM, Hunt SP, Shipley MJ, Butler SM, Riemersma RA, Turner PR. Diet and risk factors for coronary heart disease in Asians in northwest London. Lancet. 1985;2:1086–1090. - PubMed
    1. Molarius A, Seidell JC. Selection of anthropometric indicators for classification of abdominal fatness: a critical review. Int J Obes Relat Metab Disord. 1998;22:719–727. - PubMed
    1. Cheng YJ, Gregg EW, De Rekeneire N, Williams DE, Imperatore G, Caspersen CJ, Kahn HS. Muscle-strengthening activity and its association with insulin sensitivity. Diabetes Care. 2007;30:2264–2270. - PubMed
    1. Dunstan DW, Daly RM, Owen N, Jolley D, De Courten M, Shaw J, Zimmet P. High-intensity resistance training improves glycemic control in older patients with type 2 diabetes. Diabetes Care. 2002;25:1729–1736. - PubMed
    1. Epidemiologic and methodologic problems in determining nutritional status of older persons. Proceedings of a conference. Albuquerque, New Mexico, October 19-21, 1988. Am J Clin Nutr. 1989;50(5 Suppl):1121–1235. - PubMed