Pathogenesis and disease mechanisms of occupational asthma
- PMID: 21978852
- PMCID: PMC4683932
- DOI: 10.1016/j.iac.2011.07.008
Pathogenesis and disease mechanisms of occupational asthma
Abstract
Occupational asthma (OA) is one of the most common forms of work-related lung disease in all industrialized nations. The clinical management of patients with OA depends on an understanding of the multifactorial pathogenetic mechanisms that can contribute to this disease. This article discusses the various immunologic and nonimmunologic mechanisms and genetic susceptibility factors that drive the inflammatory processes of OA.
Copyright © 2011 Elsevier Inc. All rights reserved.
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