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Review
. 2011 Oct;44(5):1155-71.
doi: 10.1016/j.otc.2011.06.002. Epub 2011 Jul 21.

Skull base chordomas

Maria Koutourousiou  1 , Carl H Snyderman, Juan Fernandez-Miranda, Paul A Gardner
Affiliations
Review

Skull base chordomas

Maria Koutourousiou et al. Otolaryngol Clin North Am. 2011 Oct.

Abstract

Skull base chordomas are rare midline malignancies of clival origin that represent one of the most challenging skull base tumors to treat, given their location, invasiveness, potential extension around vital neurovascular structures, and high recurrence rate. Total tumor resection is the mainstay of treatment. The combination of surgery and postoperative irradiation appears to provide the best outcome.

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