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Review
. 2011 Oct;21(5):576-82.
doi: 10.1016/j.sbi.2011.08.005.

Mechanisms and principles of N-linked protein glycosylation

Flavio Schwarz  1 , Markus Aebi
Affiliations
Review

Mechanisms and principles of N-linked protein glycosylation

Flavio Schwarz et al. Curr Opin Struct Biol. 2011 Oct.

Abstract

N-linked glycosylation, a protein modification system present in all domains of life, is characterized by a high structural diversity of N-linked glycans found among different species and by a large number of proteins that are glycosylated. Based on structural, functional, and phylogenetic approaches, this review discusses the highly conserved processes that are at the basis of this unique general protein modification system.

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