A new link in the chain from amino acids to mTORC1 activation
- PMID: 21981914
- DOI: 10.1016/j.molcel.2011.09.004
A new link in the chain from amino acids to mTORC1 activation
Abstract
A recent study reveals that the scaffold protein p62 plays a role in linking nutritional cues (amino acids) to the activation of mammalian target of rapamycin complex 1 (mTORC1), a protein kinase that controls cell size and proliferation.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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p62 is a key regulator of nutrient sensing in the mTORC1 pathway.Mol Cell. 2011 Oct 7;44(1):134-46. doi: 10.1016/j.molcel.2011.06.038. Mol Cell. 2011. PMID: 21981924 Free PMC article.
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