Long live sox2: sox2 lasts a lifetime
- PMID: 21982223
- DOI: 10.1016/j.stem.2011.09.007
Long live sox2: sox2 lasts a lifetime
Abstract
Sox2 is a key transcription factor required for the maintenance of pluripotency in embryonic cells and morphogenesis of several epithelia. In this issue of Cell Stem Cell, Arnold et al. (2011) demonstrate that Sox2 marks long-lived adult stem cells to ensure homeostasis in a broad range of adult tissues.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice.Cell Stem Cell. 2011 Oct 4;9(4):317-29. doi: 10.1016/j.stem.2011.09.001. Cell Stem Cell. 2011. PMID: 21982232 Free PMC article.
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