MeCP2: phosphorylated locally, acting globally
- PMID: 21982363
- DOI: 10.1016/j.neuron.2011.09.017
MeCP2: phosphorylated locally, acting globally
Abstract
In this issue of Neuron, Greenberg and colleagues revise our understanding of how activity-dependent MeCP2 phosphorylation regulates distinct aspects of brain development and circuit function. The study also suggests a prominent role for MeCP2 in the regulation of global chromatin state in vivo.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function.Neuron. 2011 Oct 6;72(1):72-85. doi: 10.1016/j.neuron.2011.08.022. Neuron. 2011. PMID: 21982370 Free PMC article.
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