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. 2011 Oct 7:11:162.
doi: 10.1186/1471-244X-11-162.

Cognitive flexibility in verbal and nonverbal domains and decision making in anorexia nervosa patients: a pilot study

Giovanni Abbate-Daga  1 , Sara Buzzichelli, Federico Amianto, Giuseppe Rocca, Enrica Marzola, Shawn M McClintock, Secondo Fassino
Affiliations

Cognitive flexibility in verbal and nonverbal domains and decision making in anorexia nervosa patients: a pilot study

Giovanni Abbate-Daga et al. BMC Psychiatry. .

Abstract

Background: This paper aimed to investigate cognitive rigidity and decision making impairments in patients diagnosed with Anorexia Nervosa Restrictive type (AN-R), assessing also verbal components.

Methods: Thirty patients with AN-R were compared with thirty age-matched healthy controls (HC). All participants completed a comprehensive neuropsychological battery comprised of the Trail Making Test, Wisconsin Card Sorting Test, Hayling Sentence Completion Task, and the Iowa Gambling Task. The Beck Depression Inventory was administered to evaluate depressive symptomatology. The influence of both illness duration and neuropsychological variables was considered. Body Mass Index (BMI), years of education, and depression severity were considered as covariates in statistical analyses.

Results: The AN-R group showed poorer performance on all neuropsychological tests. There was a positive correlation between illness duration and the Hayling Sentence Completion Task Net score, and number of completion answers in part B. There was a partial effect of years of education and BMI on neuropsychological test performance. Response inhibition processes and verbal fluency impairment were not associated with BMI and years of education, but were associated with depression severity.

Conclusions: These data provide evidence that patients with AN-R have cognitive rigidity in both verbal and non-verbal domains. The role of the impairment on verbal domains should be considered in treatment. Further research is warranted to better understand the relationship between illness state and cognitive rigidity and impaired decision-making.

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References

    1. Halmi KA. The multimodal treatment of eating disorders. World Psychiatry. 2005;4(2):69–73. - PMC - PubMed
    1. Fassino S, Abbate Daga G, Amianto F, Leombruni P, Boggio S, Rovera GG. Temperament and character profile of eating disorders: a controlled study with the Temperament and Character Inventory. Int J Eat Disord. 2002;32(4):412–425. doi: 10.1002/eat.10099. - DOI - PubMed
    1. Roberts ME, Tchanturia K, Stahl D, Southgate L, Treasure J. A systematic review and meta-analysis of set-shifting ability in eating disorders. Psychol Med. 2007;37:1075–1084. doi: 10.1017/S0033291707009877. - DOI - PubMed
    1. Wade TD, Bulik CM. Shared genetic and environmental risk factors between undue influence of body shape and weight on self-evaluation and dimensions of perfectionism. Psychol Med. 2007;37(5):635–644. doi: 10.1017/S0033291706009603. - DOI - PubMed
    1. Liao PC, Uher R, Lawrence N, Treasure J, Shmidt U, Campbell IC, Collier DA, Tchanturia K. An examination of decision making in bulimia nervosa. J Clin Exp Neuropsychol. 2008;11:1–7. - PubMed

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