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. 1990 Aug;172(8):4736-40.
doi: 10.1128/jb.172.8.4736-4740.1990.

High-level expression of the FtsA protein inhibits cell septation in Escherichia coli K-12

H C Wang  1 , R C Gayda
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High-level expression of the FtsA protein inhibits cell septation in Escherichia coli K-12

H C Wang et al. J Bacteriol. 1990 Aug.

Abstract

DNA fragments encoding the ftsA gene were subcloned into plasmids downstream of a lac promoter or a tac promoter. These plasmid constructs, when transformed into wild-type and mutant strains, inhibited normal cell septation, causing the formation of long nonseptate filaments. This phenotype is due to overproduction of the FtsA protein.

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References

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