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Case Reports
. 2011 Dec;199(6):508-9.
doi: 10.1192/bjp.bp.111.092197. Epub 2011 Oct 7.

Anti-NMDA receptor encephalitis: an important differential diagnosis in psychosis

Helen Barry  1 , Orla Hardiman, Daniel G Healy, Mary Keogan, Joan Moroney, Peter P Molnar, David R Cotter, Kieran C Murphy
Affiliations
Case Reports

Anti-NMDA receptor encephalitis: an important differential diagnosis in psychosis

Helen Barry et al. Br J Psychiatry. 2011 Dec.

Abstract

We present four cases of confirmed anti-NMDA receptor encephalitis; three presented initially with serious psychiatric symptoms and the other developed significant psychiatric symptoms during the initial phase of illness. Brain biopsy findings of one patient are also described. Psychiatrists should consider anti-NMDA receptor encephalitis in patients presenting with psychosis and additional features of dyskinesias, seizures and catatonia, particularly where there is no previous history of psychiatric disorder.

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Comment in

  • Antibody-mediated encephalitis and psychosis.
    Pollak TA, Lennox BR, Vincent A, Nicholson TR. Pollak TA, et al. Br J Psychiatry. 2012 Apr;200(4):344; author reply 344-5. doi: 10.1192/bjp.200.4.344. Br J Psychiatry. 2012. PMID: 22474234 No abstract available.
  • Encephalitis and psychosis.
    Moran N. Moran N. Br J Psychiatry. 2012 May;200(5):428; author reply 428. doi: 10.1192/bjp.200.5.428. Br J Psychiatry. 2012. PMID: 22550332 No abstract available.
  • Encephalitis and schizophrenia: a matter of words.
    O'Loughlin K, Ruge P, McCauley M. O'Loughlin K, et al. Br J Psychiatry. 2012 Jul;201(1):74; author reply 74. doi: 10.1192/bjp.201.1.74. Br J Psychiatry. 2012. PMID: 22753856 No abstract available.

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