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Comment
. 2011 Sep;8(9):707.
doi: 10.1038/nmeth.1683.

More options for gene editing

Monya Baker
Comment

More options for gene editing

Monya Baker. Nat Methods. 2011 Sep.

Abstract

Engineering precise genetic changes in a genome is powerful way to study gene function, and several recent papers describe new applications of gene-editing tools. Working with researchers at Sangamo BioSciences, Howard Hughes Medical Institute investigator Barbara Meyer and her colleagues at the University of California, Berkeley, described the first systems for making targeted genomic modifications in the roundworm Caenorhabditis elegans, a valuable model organism (Wood et al., 2011).

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Comment on

  • Targeted genome editing across species using ZFNs and TALENs.
    Wood AJ, Lo TW, Zeitler B, Pickle CS, Ralston EJ, Lee AH, Amora R, Miller JC, Leung E, Meng X, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Meyer BJ. Wood AJ, et al. Science. 2011 Jul 15;333(6040):307. doi: 10.1126/science.1207773. Epub 2011 Jun 23. Science. 2011. PMID: 21700836 Free PMC article.

References

    1. Science. 2011 Jul 15;333(6040):307 - PubMed
    1. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12013-7 - PubMed
    1. Nat Biotechnol. 2011 Jul 07;29(8):731-4 - PubMed
    1. Cell. 2011 Jul 22;146(2):318-31 - PubMed

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