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Review
. 1990:13 Suppl 1:S76-83.
doi: 10.1097/00002826-199001001-00009.

Possible mechanism of antidepressant effect of L-sulpiride

G Serra  1 , A Forgione, P S D'Aquila, M Collu, W Fratta, G L Gessa
Affiliations
Review

Possible mechanism of antidepressant effect of L-sulpiride

G Serra et al. Clin Neuropharmacol. 1990.

Abstract

L-Sulpiride is a dopamine (DA)-receptor blocker that acts as an antidepressant at low doses. We have reviewed evidence suggesting that the antidepressant effect of L-sulpiride may depend on the activation of DA transmission secondary to the blockade of DA autoreceptors.

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