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. 2005 Jun 30;18(2):74-8.

Effect of early nutritional support on clinical course and septic complications in patients with severe burns

D Tancheva  1 , O Hadjiiski
Affiliations

Effect of early nutritional support on clinical course and septic complications in patients with severe burns

D Tancheva et al. Ann Burns Fire Disasters. .

Abstract
in English, French

Retrospective and prospective analyses of methods for nutritional support were carried out to assess their efficiency in covering the calculated caloric and protein needs of patients with severe burns. The energy and protein needs of the patients in Group 1 (study group) with nutritional support started 24 h after the thermal trauma were determined by the Toronto formula or by means of indirect calorimetry. Nutritional support of patients in Group 2 (control group) were initiated on day 4 post-trauma. The patients in the two groups were similar in respect to age, gender, body surface area burned, and injury severity score. We found statistically significant differences in the metabolic response of both groups as measured by nitrogen balance, serum proteins, and absolute lymphocyte count. Significant differences were also registered in body weight loss, number of positive haemocultures, and the complications rate.

Les Auteurs ont effectué des analyses rétrospectives et prospectives des méthodes de support nutritionnel pour évaluer leur capacité de couvrir les exigences calculées caloriques et protéiques des grands brûlés. Les besoins énergétiques et protéiques des patients du premier groupe 1 (groupe d'étude), qui recevaient un support nutritionnel initié 24 h après la brûlure, ont été déterminés avec la formule de Toronto ou avec la calorimétrie indirecte. Le support nutritionnel des patients du deuxième groupe (groupe témoin) a commencé quatre jour après la brûlure. Les patients des deux groupes étaient comparables pour ce qui concerne l'âge, le sexe, la surface corporelle brûlée et le score de la sévérité de la lésion. Les Auteurs ont trouvé des différences statistiquement significatives dans la réponse métabolique des deux groupes mesurée moyennant le bilan d'azote, les protéines sériques et le compte absolu des lymphocytes. Ils ont noté en outre des différences significatives dans les pertes de poids corporel, le numéro des hémocultures positives et le taux des complications.

Keywords: BURNS; CLINICAL; COMPLICATIONS; COURSE; EARLY; EFFECT; NUTRITIONAL; PATIENTS; SEPTIC; SEVERE; SUPPORT.

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Figures

Table I
Table I. Demographic analysis
Table II
Table II. Formulas used for estimation of daily energy requirements and nitrogen balance
Fig. 1
Fig. 1. Mean daily caloric intake (kcal/kg/24 h).
Fig. 2
Fig. 2. Mean daily nitrogen intake (g/kg/24 h).
Fig. 3
Fig. 3. Nitrogen balance (g/24 h).
Table III
Table III. The first day NB became positive, the number of days it remained positive, body weight loss (BWL), and the number of positive haemocultures
Fig. 4
Fig. 4. Serum albumin (g/l).
Fig. 5
Fig. 5. Absolute lymphocyte count/mm3.
Table IV
Table IV. Complications
See this image and copyright information in PMC

References

    1. Allard J.P., Pichard C. et al. Validation of a new formula for calculating the energy requirements of burn patients. JPEN. 1990;14:115–115. - PubMed
    1. Gore D.C., Chinkes D.L., Hart D.W. et al. Hyperglycaemia exacerbates muscle protein catabolism in burn-injured patients. Crit. Care Med. 2002;30:2438–2442. - PubMed
    1. Cunningham J.J., Prelack K., Sheridan R., Remennyder J.P. Nutrition support during the acute care of moderately or severely burned patients. In: Payne-James J., Grimble G., Silk D., editors. Artificial Nutrition Support in Clinical Practice. 2. London; San Francisco: 2000. pp. 575–589.
    1. Pitkänen O., Takala J., Pöyhönen M., Kari A. Nitrogen and energy balance in septic and injured intensive care patients: Response to parenteral nutrition. Clin. Nutr. 1991;10:258–265. - PubMed
    1. Takala J., Suojaranta-Ylinen R., Pitkänen O. Nutrition support in trauma and sepsis. In: Payne-James J., Grimble G., Silk D., editors. Artificial Nutrition Support in Clinical Practice. 2. London; San Francisco: 2000. pp. 575–589.

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