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Case Reports
. 2011:2011:597350.
doi: 10.5402/2011/597350. Epub 2010 Dec 28.

Digestive malacoplakia in children: case report

J Bouguila  1 , K Brahim, M Mokni, K Skandrani, A Harbi, A S Essoussi, L Boughammoura
Affiliations
Case Reports

Digestive malacoplakia in children: case report

J Bouguila et al. ISRN Gastroenterol. 2011.

Abstract

Malacoplakia is a form of chronic granulomatous inflammatory reaction that rarely affects the pediatric age group. The gastrointestinal system is the second most common site for the occurrence of malacoplakia. We report the case of a 9-year-old girl who was hospitalized for abdominal pain, chronic diarrhea, and rectal hemorrhage. The endoscopic examinations and histopathology confirmed the diagnosis of intestinal malacoplakia. We successfully treated her with oral levofloxacin. This disease does not have any specific clinical or biological signs, and the diagnosis is exclusively based on histology.

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Figures

Figure 1
Figure 1
(a) Endoscopic view showing an extended colitis with edema and thickening of mucosa, (b) bleeding rectal polyp.
Figure 2
Figure 2
(a) Diffuse infiltration of the colonic mucosa by numerous histiocytes with cy toplasmic inclusions, (b) lesion which stain positively with periodic acid-Schiff, Von Kossa, and Prussian blue stains: Michaelis-Gutmann bodies.
Figure 3
Figure 3
Endoscopic view after two years of treatment showing a normal intestinal mucosa.
See this image and copyright information in PMC

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