Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2011:2011:608901.
doi: 10.5402/2011/608901. Epub 2011 Jan 17.

Eosinophilic enterocolitis diagnosed by means of upper endoscopy and colonoscopy with random biopsies treated with budenoside: a case report and review of the literature

Ghulamullah Shahzad  1 , Duane Moise, Seth Lipka, Kaleem Rizvon, Paul J Mustacchia
Affiliations
Case Reports

Eosinophilic enterocolitis diagnosed by means of upper endoscopy and colonoscopy with random biopsies treated with budenoside: a case report and review of the literature

Ghulamullah Shahzad et al. ISRN Gastroenterol. 2011.

Abstract

Intense infiltration of gastrointestinal and colonic mucosa with eosinophils or acidophilic gastroenteritis (EG) is a relatively uncommon picture for a pathologist endoscopist especially outside the pediatric age group and is highly suggestive of an ongoing chronic inflammatory process. Existing literature projected a hypothetical association with allergy but the exact pathophysiology is still unknown. Association with malabsorption, protein losing enteropathy, and refractory ulcers with gastrointestinal bleeding makes the clinical presentation more complicated. We present a unique case of diarrhea and abdominal pain in the clinical presentation with associated peripheral eosinophilia, asthma, and gastroesophageal reflux disease (GERD). The patient's symptoms abated after initiation of budesonide.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Unremarkable cecal mucosa.
Figure 2
Figure 2
Eosinophilic infiltration.
See this image and copyright information in PMC

References

    1. Rothenberg ME. Eosinophilic gastrointestinal disorders (EGID) Journal of Allergy and Clinical Immunology. 2004;113(1):11–29. - PubMed
    1. Talley NJ, Shorter RG, Phillips SF, Zinsmeister AR. Eosinophilic gastroenteritis: a clinicopathological study of patients with disease of the mucosa, muscle layer, and subserosal tissues. Gut. 1990;31(1):54–58. - PMC - PubMed
    1. Kelly KJ. Eosinophilic gastroenteritis. Journal of Pediatric Gastroenterology and Nutrition. 2000;30(1):S28–S35. - PubMed
    1. Kaisjer R. Zur Kenntinis der allergischen Affektionen des Verdaungskanals vom Standput des Chrirurgen aus. Arch Klin Chir. 1937;188:36–64.
    1. Guajardo JR, Plotnick LM, Fende JM, Collins MH, Putnam PE, Rothenberg ME. Eosinophil-associated gastrointestinal disorders: a world-wide-web based registry. Journal of Pediatrics. 2002;141(4):576–581. - PubMed

Publication types

LinkOut - more resources