Reshaping the future of nanopharmaceuticals: ad iudicium
- PMID: 21992178
- DOI: 10.1021/nn2038252
Reshaping the future of nanopharmaceuticals: ad iudicium
Abstract
We present views on the future development of biologics-based nanopharmaceuticals from a "high risk-high gain" perspective and within the context of personalized therapies. Integrated scientific, commercial, and societal aspects are addressed, and provocative combined realistic biotech, computational, and nanotech approaches for tailor-made engineering of nanopharmaceuticals are discussed.
© 2011 American Chemical Society
Similar articles
-
Ask the experts: future of the pharmaceutical industry. Interview by Future Medicinal Chemistry.Future Med Chem. 2011 Nov;3(15):1863-72. doi: 10.4155/fmc.11.145. Future Med Chem. 2011. PMID: 22023030
-
Personalized medicine: changing the paradigm of drug development.Methods Mol Biol. 2012;823:367-78. doi: 10.1007/978-1-60327-216-2_24. Methods Mol Biol. 2012. PMID: 22081358
-
Nanomedicine: application of nanobiotechnology in medical practice.Med Princ Pract. 2008;17(2):89-101. doi: 10.1159/000112961. Epub 2008 Feb 19. Med Princ Pract. 2008. PMID: 18287791 Review.
-
What is next for small-molecule drug discovery?Future Med Chem. 2009 Sep;1(6):1029-36. doi: 10.4155/fmc.09.72. Future Med Chem. 2009. PMID: 21425992
-
Nanobiotechnology and personalized medicine.Prog Mol Biol Transl Sci. 2011;104:325-54. doi: 10.1016/B978-0-12-416020-0.00008-5. Prog Mol Biol Transl Sci. 2011. PMID: 22093223 Review.
Cited by
-
Real-time analysis of composite magnetic nanoparticle disassembly in vascular cells and biomimetic media.Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4245-50. doi: 10.1073/pnas.1324104111. Epub 2014 Mar 3. Proc Natl Acad Sci U S A. 2014. PMID: 24591603 Free PMC article.
-
What is the role of curvature on the properties of nanomaterials for biomedical applications?Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016 May;8(3):334-54. doi: 10.1002/wnan.1365. Epub 2015 Aug 27. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016. PMID: 26310432 Free PMC article. Review.
-
Antimicrobial Nanotubes: From Synthesis and Promising Antimicrobial Upshots to Unanticipated Toxicities, Strategies to Limit Them, and Regulatory Issues.Nanomaterials (Basel). 2025 Apr 21;15(8):633. doi: 10.3390/nano15080633. Nanomaterials (Basel). 2025. PMID: 40278498 Free PMC article. Review.
-
Nanoparticles for imaging, sensing, and therapeutic intervention.ACS Nano. 2014 Apr 22;8(4):3107-22. doi: 10.1021/nn500962q. Epub 2014 Mar 18. ACS Nano. 2014. PMID: 24641589 Free PMC article. Review.
-
Structural characterization of lipidic systems under nonequilibrium conditions.Eur Biophys J. 2012 Oct;41(10):831-40. doi: 10.1007/s00249-012-0815-7. Epub 2012 May 9. Eur Biophys J. 2012. PMID: 22569535 Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources