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. 2009 Sep;1(2):91-103.
doi: 10.3390/v1020091. Epub 2009 Jul 27.

HBV-Specific Adaptive Immunity

Antonio Bertoletti  1   2   3 , Anthony T Tan  1 , Adam J Gehring  1
Affiliations

HBV-Specific Adaptive Immunity

Antonio Bertoletti et al. Viruses. 2009 Sep.

Abstract

The successful control of HBV infection requires an efficient expansion of distinct elements of the adaptive immune system (B cells, helper and cytotoxic T cells) that, due to the hepatotropic nature of HBV, need to operate in the liver parenchyma. In this respect, we will discuss broad features of HBV immunity in patients with resolved or chronic HBV infection and analyze how the liver environment can directly modulate HBV-immunity.

Keywords: B cells; HBV; T cells.

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Figures

Figure 1.
Figure 1.
Anti-viral adaptive immune response during HBV infection.
See this image and copyright information in PMC

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