Use of administrative claims data for comparative effectiveness research of rheumatoid arthritis treatments
- PMID: 21996148
- PMCID: PMC3308086
- DOI: 10.1186/ar3472
Use of administrative claims data for comparative effectiveness research of rheumatoid arthritis treatments
Abstract
Observational studies, particularly those using large administrative claims databases, have become increasingly popular sources of comparative effectiveness or comparative safety research. Studies using claims data often face challenges and criticisms due to the lack of certain clinical information, such as lifestyle risk factors, disease severity, and questionable accuracy of disease diagnoses. A novel, claims-based algorithm to evaluate the clinical effectiveness of rheumatoid arthritis medications has been developed and its performance seems promising, although further validation is needed.
Comment on
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Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis.Arthritis Res Ther. 2011;13(5):R155. doi: 10.1186/ar3471. Epub 2011 Sep 20. Arthritis Res Ther. 2011. PMID: 21933396 Free PMC article.
References
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- Curtis JR, Baddley JW, Yang S, Patkar N, Chen L, Delzell E, Mikuls TR, Saag KG, Singh J, Safford M, Cannon GW. Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis. Arthritis Res Ther. 2011;13:R155. doi: 10.1186/ar3471. - DOI - PMC - PubMed
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- Institute of Medicine. Initial National Priorities for Comparative Effectiveness Research. Washington, DC: Institute of Medicine; 2009.
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- Curtis JR, Jain A, Askling J, Bridges SL Jr, Carmona L, Dixon W, Finckh A, Hyrich K, Greenberg JD, Kremer J, Listing J, Michaud K, Mikuls T, Shadick N, Solomon DH, Weinblatt ME, Wolfe F, Zink A. A comparison of patient characteristics and outcomes in selected European and U.S. rheumatoid arthritis registries. Semin Arthritis Rheum. 2010;40:2–14. doi: 10.1016/j.semarthrit.2010.03.003. - DOI - PMC - PubMed
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