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. 2011 Oct;17(10):1897-9.
doi: 10.3201/eid1710.110629.

Seroconversion to pandemic (H1N1) 2009 virus and cross-reactive immunity to other swine influenza viruses

Ranawaka A P M Perera  1 , Steven Riley, Siu K Ma, Hua-Chen Zhu, Yi Guan, Joseph S M Peiris
Affiliations

Seroconversion to pandemic (H1N1) 2009 virus and cross-reactive immunity to other swine influenza viruses

Ranawaka A P M Perera et al. Emerg Infect Dis. 2011 Oct.

Abstract

To assess herd immunity to swine influenza viruses, we determined antibodies in 28 paired serum samples from participants in a prospective serologic cohort study in Hong Kong who had seroconverted to pandemic (H1N1) 2009 virus. Results indicated that infection with pandemic (H1N1) 2009 broadens cross-reactive immunity to other recent subtype H1 swine viruses.

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Figures

Figure
Figure
Neutralizing antibody titers to subtype H1 swine influenza viruses of the classical swine, North American triple reassortant, and Eurasian avian-like swine lineages in baseline (prepandemic [pre]) and convalescent-phase (postpandemic [post]) serum samples from 28 persons who seroconverted to pandemic (H1N1) 2009 infection, Hong Kong. Complete details on the serologic study cohort from which this subset is drawn are from (4). The pandemic A/California/4/2009 (H1N1) and seasonal influenza A/HK/400599/2008 (H1N1) viruses were used as controls. Orange lines indicate geometric mean titer; green error bars indicate 95% confidence intervals. *p<0.05; †p<0.01.
See this image and copyright information in PMC

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