Review
Fluoxetine and its two enantiomers as selective serotonin uptake inhibitors
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- PMID: 2200429
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Review
Fluoxetine and its two enantiomers as selective serotonin uptake inhibitors
Acta Pharm Nord.
1990.
Abstract
The biochemical and pharmacological profiles of R,S-fluoxetine and its R and S enantiomers have been compared and reviewed. Both enantiomers exhibit profiles analogous to R,S-fluoxetine as inhibitors of serotonin uptake in vitro and in vivo with about equal potencies or a eudismic ratio near unity.
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