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Review
. 1990 Jul 31;191(2):257-61.
doi: 10.1111/j.1432-1033.1990.tb19118.x.

Translation and regulation of translation in the yeast Saccharomyces cerevisiae

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Free article
Review

Translation and regulation of translation in the yeast Saccharomyces cerevisiae

P P Müller et al. Eur J Biochem. .
Free article

Abstract

In recent years the yeast Saccharomyces cerevisiae has become a model system for studies of eukaryotic translation and translation regulation. Analysis of mRNA structure, translation initiation factor sequences and the translation initiation pathway indicate, that translation in S. cerevisiae is very similar to translation in higher eukaryotes. The availability of powerful genetic techniques lead to the dissection in yeast of individual steps in the translation pathway, the detection of biochemical interactions between components involved in translation and the unravelling of complex regulation phenomena.

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