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. 2012:2012:268123.
doi: 10.1155/2012/268123. Epub 2011 Oct 5.

Histoplasma virulence and host responses

Mircea Radu Mihu  1 , Joshua Daniel Nosanchuk
Affiliations

Histoplasma virulence and host responses

Mircea Radu Mihu et al. Int J Microbiol. 2012.

Abstract

Histoplasma capsulatum is the most prevalent cause of fungal respiratory disease. The disease extent and outcomes are the result of the complex interaction between the pathogen and a host's immune system. The focus of our paper consists in presenting the current knowledge regarding the multiple facets of the dynamic host-pathogen relationship in the context of the virulence arsenal displayed by the fungus and the innate and adaptive immune responses of the host.

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References

    1. Darling ST. The morphology of the parasite (Histoplasma capsulatum) and the lesions of histoplasmosis, a fatal disease of tropical America. Journal of Experimental Medicine. 1909;11(4):515–531. - PMC - PubMed
    1. Wheat LJ, Kauffman CA. Histoplasmosis. Infectious Disease Clinics of North America. 2003;17(1):1–19. - PubMed
    1. http://www.cdc.gov/nczved/divisions/dfbmd/diseases/histoplasmosis.
    1. Goodwin RA, Loyd JE, Des Prez RM. Histoplasmosis in normal hosts. Medicine. 1981;60(4):231–266. - PubMed
    1. Deepe GS., Jr. The immune response to Histoplasma capsulatum: unearthing its secrets. Journal of Laboratory and Clinical Medicine. 1994;123(2):201–205. - PubMed

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