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. 2011 Nov;59(5):1018-23.
doi: 10.1111/j.1365-2559.2011.03959.x. Epub 2011 Oct 18.

Ovarian histopathological and ubiquitin-immunophenotypic features in fragile X-associated primary ovarian insufficiency: a study of five cases and selected controls

Martin C Chang, John J DeCaro, Mei Zheng, Marla Gearing, Lisa Shubeck, Stephanie L Sherman, Corrine K Welt

Ovarian histopathological and ubiquitin-immunophenotypic features in fragile X-associated primary ovarian insufficiency: a study of five cases and selected controls

Martin C Chang et al. Histopathology. 2011 Nov.
No abstract available

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Figures

Figure 1
Figure 1
A, Ovary of a fragile X premutation carrier with 100 repeats demonstrating frequent ubiquitin-positive inclusions (arrows). Non-specific staining of stromal nuclei and cytoplasm is also seen. B, Ovary of a control case showing a rare ubiquitin-positive inclusion (arrow). (Ubiquitin stains, haematoxylin counterstain; photographed under ×40 objective and ×0.70 C-Mount adapter.)
Figure 2
Figure 2
Ovarian follicles including granulosa and theca cells found in (A) a fragile X premutation carrier with 62 repeats and (B) a control patient, showing similar morphology and ubiquitin immunostaining patterns. (Ubiquitin stains, haematoxylin counterstain; photographed under ×40 objective and ×0.70 C-Mount adapter).
See this image and copyright information in PMC

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