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. 2011 Nov;49(11):705-8.
doi: 10.5414/cp201588.

Systemic steroids in acute exacerbation of COPD - from guidelines to bedside

P-H Wang  1 , S-L Cheng, H-C Wang, H-T Chang, Y-L Hsu, Y-S Chen, C-Y Chang
Affiliations

Systemic steroids in acute exacerbation of COPD - from guidelines to bedside

P-H Wang et al. Int J Clin Pharmacol Ther. 2011 Nov.

Abstract

The optimal steroid dosages in AECOPD are still under debate. Admission records of patients in our hospital from January to December 2008 due to a diagnosis of AECOPD were reviewed. More wheezing and tachypnea were noted in the patients with a maximal daily prednisolone dose more than 60 mg. The steroid dose was higher in AECOPD without pneumonia than those concurrent with pneumonia. Those who had concurrent pneumonia had a higher risk of nosocomial infections. The study reflects the heterogeneity of AECOPD and that steroid dosages were determined by the clinical evaluation of the severity of illness and bacterial infections.

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