doi: 10.1039/c1ob06619f.
Epub 2011 Oct 20.
Transannular Claisen rearrangement reactions for the synthesis of vinylcyclobutanes: formal synthesis of (±)-grandisol
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- PMID: 22011731
- DOI: 10.1039/c1ob06619f
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Transannular Claisen rearrangement reactions for the synthesis of vinylcyclobutanes: formal synthesis of (±)-grandisol
Org Biomol Chem.
.
Abstract
Unsaturated eight-membered lactones undergo decarboxylative and non-decarboxylative transannular Ireland-Claisen rearrangement reactions, to give substituted vinylcyclobutanes. A formal synthesis of (±)-grandisol is described.
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