Comment on

• A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28.

  Kong KF, Yokosuka T, Canonigo-Balancio AJ, Isakov N, Saito T, Altman A. Kong KF, et al. Nat Immunol. 2011 Oct 2;12(11):1105-12. doi: 10.1038/ni.2120. Nat Immunol. 2011. PMID: 21964608 Free PMC article.
• The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells.

  Chuang HC, Lan JL, Chen DY, Yang CY, Chen YM, Li JP, Huang CY, Liu PE, Wang X, Tan TH. Chuang HC, et al. Nat Immunol. 2011 Oct 9;12(11):1113-8. doi: 10.1038/ni.2121. Nat Immunol. 2011. PMID: 21983831