Driving with no brakes: molecular pathophysiology of Kv7 potassium channels
- PMID: 22013194
- DOI: 10.1152/physiol.00009.2011
Driving with no brakes: molecular pathophysiology of Kv7 potassium channels
Abstract
Kv7 potassium channels regulate excitability in neuronal, sensory, and muscular cells. Here, we describe their molecular architecture, physiological roles, and involvement in genetically determined channelopathies highlighting their relevance as targets for pharmacological treatment of several human disorders.
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