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Review
. 2011 Oct;26(5):365-76.
doi: 10.1152/physiol.00009.2011.

Driving with no brakes: molecular pathophysiology of Kv7 potassium channels

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Free article
Review

Driving with no brakes: molecular pathophysiology of Kv7 potassium channels

Maria Virginia Soldovieri et al. Physiology (Bethesda). 2011 Oct.
Free article

Abstract

Kv7 potassium channels regulate excitability in neuronal, sensory, and muscular cells. Here, we describe their molecular architecture, physiological roles, and involvement in genetically determined channelopathies highlighting their relevance as targets for pharmacological treatment of several human disorders.

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