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Comment
. 2011 Jul;1(2):100-2.
doi: 10.1158/2159-8290.CD-11-0117.

The first line of intra-abdominal metastatic attack: breaching the mesothelial cell layer

Affiliations
Comment

The first line of intra-abdominal metastatic attack: breaching the mesothelial cell layer

Hilary A Kenny et al. Cancer Discov. 2011 Jul.

Abstract

Iwanicki and colleagues reveal that ovarian cancer spheroids clear mesothelial cells which cover the surface of the abdominal cavity using myosin-generated force.

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Figures

Figure 1
Figure 1. Ovarian cancer cell metastasis
Hematoxylin and eosin stained image of human peritoneal surface from a cancer-free patient and a microscopic tumor implant on the omental surface from a patient with metastatic serous ovarian carcinoma. Note, mesothelial cells (arrows) line the abdominal surface but are not detected under the proliferating ovarian cancer cell implant (asterisk).

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