Phencyclidine
- PMID: 2201519
Phencyclidine
Abstract
Patients intoxicated with phencyclidine (PCP) present both diagnostic and management dilemmas. The clinical presentation ranges from coma to severe agitation and violence; disorientation, psychosis, catatonia and bizarre behavior can be seen. Patients are at-risk for significant medical complications such as rhabdomyolysis, seizures, and hyperthermia. This article reviews the effects and complications of PCP abuse and offers an approach to the management of these patients.
Similar articles
-
The diagnosis and treatment of the PCP abuse syndrome.NIDA Res Monogr. 1978 Aug;(21):229-40. NIDA Res Monogr. 1978. PMID: 101871 No abstract available.
-
Rhabdomyolysis and acute renal failure associated with phencyclidine intoxication.Arch Intern Med. 1980 Apr;140(4):568-9. Arch Intern Med. 1980. PMID: 7362395
-
Opioids and designer drugs.Emerg Med Clin North Am. 1990 Aug;8(3):495-511. Emerg Med Clin North Am. 1990. PMID: 2201517 Review.
-
[Phencyclidine abuse, dependence, intoxication, and psychosis].Nihon Rinsho. 2010 Aug;68(8):1511-5. Nihon Rinsho. 2010. PMID: 20715485 Review. Japanese.
-
Phencyclidine abuse mimicking head injury.JAMA. 1980 Jun 13;243(22):2323-4. JAMA. 1980. PMID: 7373800
Cited by
-
In reply:West J Emerg Med. 2012 Dec;13(6):536-7. doi: 10.5811/westjem.2012.7.12773. West J Emerg Med. 2012. PMID: 23875056 Free PMC article. No abstract available.
-
Schizophrenia proteomics: biomarkers on the path to laboratory medicine?Diagn Pathol. 2006 Jul 17;1:11. doi: 10.1186/1746-1596-1-11. Diagn Pathol. 2006. PMID: 16846510 Free PMC article.
-
Anti-N-Methyl-D-Aspartate Receptor Encephalitis: Neuropsychiatric and Multidisciplinary Approach to a Patient Not Responding to First-Line Treatment.Cureus. 2022 Jun 8;14(6):e25751. doi: 10.7759/cureus.25751. eCollection 2022 Jun. Cureus. 2022. PMID: 35812576 Free PMC article.
-
Vaccines against drugs of abuse: a viable treatment option?Drugs. 2003;63(4):341-52. doi: 10.2165/00003495-200363040-00001. Drugs. 2003. PMID: 12558457 Review.
-
Changes in gene expression after phencyclidine administration in developing rats: a potential animal model for schizophrenia.Int J Dev Neurosci. 2011 May;29(3):351-8. doi: 10.1016/j.ijdevneu.2010.07.234. Epub 2010 Aug 5. Int J Dev Neurosci. 2011. PMID: 20691775 Free PMC article.