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Comment
. 2011;16(11):1482-3.
doi: 10.1634/theoncologist.2011-0325. Epub 2011 Oct 20.

Impact of multigene assays in early stage breast cancer

Affiliations
Comment

Impact of multigene assays in early stage breast cancer

Shelly S Lo et al. Oncologist. 2011.

Abstract

The study of Joh et al., published in this issue of The Oncologist is reviewed.

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Conflict of interest statement

Disclosures: Shelly Lo: None; Kathy Albain: Genomic Health (C/A).

Comment on

References

    1. Sotiriou C, Pusztai L. Gene-expression signatures in breast cancer. N Engl J Med. 2009;360:790–800. - PubMed
    1. Albain KS, Paik S, van't Veer L. Prediction of adjuvant chemotherapy benefit in endocrine responsive, early breast cancer using multigene assays. Breast. 2009;18(suppl 3):S141–S145. - PubMed
    1. Paik S, Tang G, Shak S, et al. Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor–positive breast cancer. J Clin Oncol. 2006;24:3726–3734. - PubMed
    1. Albain KS, Barlow WE, Shak S, et al. Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: A retrospective analysis of a randomised trial. Lancet Oncol. 2010;11:55–65. - PMC - PubMed
    1. Joh JE, Esposito NN, Kiluk JV, et al. The effect of Oncotype DX® recurrence score on treatment recommendations for patients with estrogen receptor positive early stage breast cancer and correlation with estimation of recurrence risk by breast cancer specialists. The Oncologist. 2011;16:1520–1526. - PMC - PubMed

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