Review
Epub 2011 Oct 21.
Glucocorticoid-induced osteoporosis
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- PMID: 22018192
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Review
Glucocorticoid-induced osteoporosis
Clin Exp Rheumatol.
2011 Sep-Oct.
Abstract
Glucocorticoid-induced osteoporosis is one of the most important side-effects of glucocorticoid use, leading to an increased fracture risk. In this review, recent advances in the understanding of the mechanisms of glucocorticoid-induced osteoporosis are summarised. Methods to identify persons at risk for fractures are discussed, as well as the new ACR recommendations for the prevention and treatment of glucocorticoid-induced osteoporosis (2010). Different treatment options are summarised considering the pathogenesis of glucocorticoid-induced osteoporosis. Improved insights into pathogenesis might result in development of new treatment possibilities.
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