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. 1990 Jul;51(7):1095-9.

Prophylactic effects of recombinant bovine interferon-alpha I1 on acute Salmonella typhimurium infection in calves

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  • PMID: 2202241
Free article

Prophylactic effects of recombinant bovine interferon-alpha I1 on acute Salmonella typhimurium infection in calves

J E Peel et al. Am J Vet Res. 1990 Jul.
Free article

Abstract

The in vivo effects of a single prophylactic dose of recombinant bovine interferon (rBoIFN)-alpha I1 in calves with salmonellosis were investigated, using a Salmonella typhimurium infection model. Treatment with rBoIFN-alpha I1 reduced the degree of septicemia compared with that in control groups, and, in one experiment, using disease of reduced severity, body temperature was lower in treated calves than in controls.

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