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Case Reports
. 2012 Feb;12(2):170-3.
doi: 10.1089/vbz.2011.0708. Epub 2011 Oct 24.

Putative canine origin of rotavirus strain detected in a child with diarrhea, Taiwan

Fang-Tzy Wu  1 , Krisztián Bányai, Jen-Shiou Lin, Ho-Sheng Wu, Chao Agnes Hsiung, Yhu-Chering Huang, Kao-Pin Hwang, Baoming Jiang, Jon R Gentsch
Affiliations
Case Reports

Putative canine origin of rotavirus strain detected in a child with diarrhea, Taiwan

Fang-Tzy Wu et al. Vector Borne Zoonotic Dis. 2012 Feb.

Abstract

Rotavirus G3P[3] strains have been reported from a variety of species including humans, cats, dogs, monkeys, goats, and cows. Here, we report the characterization of the first human G3P[3] rotavirus from East Asia identified in a 2-year-old child who was treated in a hospital's emergency ward in Taiwan in February 2005. Sequence and phylogenetic analysis demonstrated a close genetic relationship between the VP4, VP6, VP7, and NSP4 genes of Taiwanese G3P[3] strain 04-94s51 and an Italian canine strain isolated a decade ago, suggesting a canine origin for the Taiwanese strain. In contrast, the Taiwanese strain was only moderately related to well-characterized canine-origin human G3P[3] strains Ro1845 and HCR3, suggesting a distinct origin for the rotavirus strain from Taiwan.

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Figures

FIG. 1.
FIG. 1.
Maximum-likelihood trees of rotavirus VP7, VP4, VP6, and NSP4 genes. Arrows indicate the G3P[3] strain, 04-94s51, identified in Taiwan. Bootstrap values >60 are indicated.
See this image and copyright information in PMC

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