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. 1990 Sep 1;40(5):1161-4.
doi: 10.1016/0006-2952(90)90510-r.

Thyroid hormone analogue SKF L-94901: effects on amino acid and carbohydrate metabolism in rat skeletal muscle in vitro

B Leighton  1 , G D Dimitriadis, M Parry-Billings, J Bond, P Kemp, E A Newsholme
Affiliations

Thyroid hormone analogue SKF L-94901: effects on amino acid and carbohydrate metabolism in rat skeletal muscle in vitro

B Leighton et al. Biochem Pharmacol. .

Abstract

In summary, hyperthyroidism increased the rate of glycolysis and decreased glycogen synthesis in isolated incubated rat soleus muscle preparations. SKF 901 also increased glycolysis, but the stimulation was 5-fold less than in T3-treated muscles. Hyperthyroidism increased the rate of glutamine release from skeletal muscle, but SKF 901 did not affect glutamine metabolism.

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