Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2011 Jul;14(3):208-10.
doi: 10.4103/0972-2327.85898.

Cysticercosis of midbrain presenting with fluctuating ptosis

Affiliations
Case Reports

Cysticercosis of midbrain presenting with fluctuating ptosis

M Netravathi et al. Ann Indian Acad Neurol. 2011 Jul.

Abstract

Fluctuating ptosis is usually caused by Myasthenia gravis. There are a few case reports of central causes of fluctuating ptosis. A 58-year-old man presented with fluctuating ptosis of one year duration. He was diagnosed as having ocular myasthenia and investigated. On evaluation, his electrophysiological tests revealed negative decremental response and results of neostigmine test was negative. During follow-up, patient developed headache. Imaging of the brain revealed midbrain cysticercosis granuloma. The focal encephalitis and edema was responsible for fluctuating ptosis. It is therefore essential to be aware of conditions that cause such pseudomyasthenic features. Patients with ptosis need to be evaluated for other rare central cause especially when neostigmine test is negative.

Keywords: Midbrain; myasthenia; neurocysticercosis; pseudomyasthenia; ptosis.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: Nil

Figures

Figure 1
Figure 1
MRI brain (a) T1-weighted sequence showing hyperintense rim with scolex showing, (b) Diffusion-weighted sequence showing scolex within the ring lesion, (c) T1-weighted image with gadolinum enhancement showing contrast enhancing ring and scolex and (d) Constructive Interference Steady state (CISS) 3D sequence showing the cystic lesion

Similar articles

Cited by

  • Bilateral ptosis: an atypical presentation of neurocysticercosis.
    Naphade PU, Singh MK, Garg RK, Rai D. Naphade PU, et al. BMJ Case Rep. 2012 Jul 25;2012:bcr2012006195. doi: 10.1136/bcr-2012-006195. BMJ Case Rep. 2012. PMID: 22843753 Free PMC article.
  • Cysticercosis and ptosis.
    Wiwanitkit S, Wiwanitkit V. Wiwanitkit S, et al. Ann Indian Acad Neurol. 2012 Jan;15(1):68. doi: 10.4103/0972-2327.93291. Ann Indian Acad Neurol. 2012. PMID: 22412281 Free PMC article. No abstract available.

References

    1. Meriggioli MN, Sanders DB. Autoimmune myasthenia gravis: Emerging clinical and biological heterogeneity. Lancet Neurol. 2009;8:475–90. - PMC - PubMed
    1. Del Brutto OH, Rajshekhar V, White AC, Jr, Tsang VC, Nash TE, Takayanagui OM, et al. Proposed diagnostic criteria for neurocysticercosis. Neurology. 2001;57:177–83. - PMC - PubMed
    1. Juel VC, Massey JM. Myasthenia gravis. Orphanet J Rare Dis. 2007;2:44. - PMC - PubMed
    1. Tummala RP, Harrison A, Madison MT, Nussbaum ES. Pseudomyasthenia resulting from a posterior carotid artery wall aneurysm: A novel presentation: A case report. Neurosurgery. 2001;49:1466–8. - PubMed
    1. Ajtai B, Fine EJ, Lincoff N. Pupil-sparing, painless compression of the oculomotor nerve by expanding basilar artery aneurysm: A case of ocular pseudomyasthenia. Arch Neurol. 2004;61:1448–50. - PubMed

Publication types