In vivo two-photon microscopy to 1.6-mm depth in mouse cortex
- PMID: 22029361
- DOI: 10.1117/1.3646209
In vivo two-photon microscopy to 1.6-mm depth in mouse cortex
Abstract
Deep tissue in vivo two-photon fluorescence imaging of cortical vasculature in a mouse brain using 1280-nm excitation is presented. A record imaging depth of 1.6 mm in mouse cortex is achieved in vivo, approximately reaching the fundamental depth limit in scattering tissue.
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