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Comment
. 2011 Oct 25;21(20):R859-60.
doi: 10.1016/j.cub.2011.09.022.

Transcriptional repressors: shutting off gene expression at the source affects developmental dynamics

David N Arnosti  1
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Transcriptional repressors: shutting off gene expression at the source affects developmental dynamics

David N Arnosti. Curr Biol. .
Free article

Abstract

Developmental networks feature genes interlinked by transcriptional activation and repression. A new study indicates that repressors can 'shut the door' to newly initiating polymerases, allowing longer target genes to produce latent transcripts after shorter genes have been effectively silenced.

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