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. 2011 Nov;86(11):1113-23.
doi: 10.4065/mcp.2011.0358.

Antimicrobial stewardship

Shira Doron  1 , Lisa E Davidson
Affiliations

Antimicrobial stewardship

Shira Doron et al. Mayo Clin Proc. 2011 Nov.

Abstract

Antimicrobial resistance is increasing; however, antimicrobial drug development is slowing. Now more than ever before, antimicrobial stewardship is of the utmost importance as a way to optimize the use of antimicrobials to prevent the development of resistance and improve patient outcomes. This review describes the why, what, who, how, when, and where of antimicrobial stewardship. Techniques of stewardship are summarized, and a plan for implementation of a stewardship program is outlined.

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References

    1. NNIS System; Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2003, issued August 2003. Am J Infect Control. 2003;31(8):481-498 - PubMed
    1. Kallen AJ, Mu Y, Bulens S, et al. Health care-associated invasive MRSA infections, 2005-2008. JAMA. 2010;304(6):641-648 - PubMed
    1. Hageman JC, Patel JB, Carey RC, Tenover FC, McDonald LC. Investigation and control of vancomycin-intermediate and -resistant Staphylococcus aureus (VISA/VRSA): a guide for health departments and infection control personnel. http://www.cdc.gov/ncidod/dhqp/pdf/ar/visa_vrsa_guide.pdf 2006. Accessed September 7, 2011
    1. Kallen AJ, Srinivasan A. Current epidemiology of multidrug-resistant gram-negative bacilli in the United States. Infect Control Hosp Epidemiol. 2010;31(i):S51-S54 - PubMed
    1. Rossi F, Baquero F, Hsueh PR, et al. In vitro susceptibilities of aerobic and facultatively anaerobic Gram-negative bacilli isolated from patients with intra-abdominal infections worldwide: 2004 results from SMART (Study for Monitoring Antimicrobial Resistance Trends). J Antimicrob Chemother. 2006;58(1):205-210 - PubMed

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