Artemisinin: the gifts from traditional Chinese medicine not only for malaria control but also for schistosomiasis control
- PMID: 22033738
- DOI: 10.1007/s00436-011-2707-7
Artemisinin: the gifts from traditional Chinese medicine not only for malaria control but also for schistosomiasis control
Abstract
The 2011 Lasker~DeBakey Clinical Medical Research Award honors the Chinese scientist Tu Youyou who discovered artemisinin and its utility for treating malaria. A therapy based on artemisinin has saved millions of lives across the globe, especially in the developing world. Meanwhile, artemisinin and its derivatives, especially for artemether and artesunate, are showing promising preventive efficacies as high as 65-97% administrated with multiple doses at 6 mg/kg body weight by 1- or 2-week intervals for preventing schistosomiasis japonica during epidemic seasons used in China for more than one decade. So, we would like to say, to our excitement, artemisinin and its derivatives are the gifts from traditional Chinese medicine not only for malaria control but also for schistosomiasis control.
Similar articles
-
New uses for old drugs: the tale of artemisinin derivatives in the elimination of schistosomiasis japonica in China.Molecules. 2014 Sep 19;19(9):15058-74. doi: 10.3390/molecules190915058. Molecules. 2014. PMID: 25244286 Free PMC article. Review.
-
Artemisinin: discovery from the Chinese herbal garden.Cell. 2011 Sep 16;146(6):855-8. doi: 10.1016/j.cell.2011.08.024. Epub 2011 Sep 9. Cell. 2011. PMID: 21907397 Free PMC article.
-
From branch to bedside: Youyou Tu is awarded the 2011 Lasker~DeBakey Clinical Medical Research Award for discovering artemisinin as a treatment for malaria.J Clin Invest. 2011 Oct;121(10):3768-73. doi: 10.1172/jci60887. J Clin Invest. 2011. PMID: 22059236 Free PMC article. No abstract available.
-
Artemisinin-A Gift from Traditional Chinese Medicine to the World (Nobel Lecture).Angew Chem Int Ed Engl. 2016 Aug 22;55(35):10210-26. doi: 10.1002/anie.201601967. Epub 2016 Aug 4. Angew Chem Int Ed Engl. 2016. PMID: 27488942 Review.
-
[Combined antimalarial therapy using artemisinin].Parassitologia. 2004 Jun;46(1-2):85-7. Parassitologia. 2004. PMID: 15305693 Review. Italian.
Cited by
-
New uses for old drugs: the tale of artemisinin derivatives in the elimination of schistosomiasis japonica in China.Molecules. 2014 Sep 19;19(9):15058-74. doi: 10.3390/molecules190915058. Molecules. 2014. PMID: 25244286 Free PMC article. Review.
-
LC-UV/MS quality analytics of paediatric artemether formulations.J Pharm Anal. 2014 Feb;4(1):37-52. doi: 10.1016/j.jpha.2013.03.006. Epub 2013 Apr 25. J Pharm Anal. 2014. PMID: 29403867 Free PMC article.
-
Haemin enhances the in vivo efficacy of artemether against juvenile and adult Schistosoma mansoni in mice.Parasitol Res. 2013 May;112(5):2005-15. doi: 10.1007/s00436-013-3358-7. Epub 2013 Feb 28. Parasitol Res. 2013. PMID: 23455942
-
Structure-function analysis of apical membrane-associated molecules of the tegument of schistosome parasites of humans: prospects for identification of novel targets for parasite control.Br J Pharmacol. 2015 Apr;172(7):1653-63. doi: 10.1111/bph.12898. Epub 2014 Dec 23. Br J Pharmacol. 2015. PMID: 25176442 Free PMC article. Review.
-
SSPH I, a Novel Anti-Cancer Saponin, Inhibits Autophagy and Induces Apoptosis via ROS Accumulation and ERK1/2 Signaling Pathway in Hepatocellular Carcinoma Cells.Onco Targets Ther. 2020 Jun 23;13:5979-5991. doi: 10.2147/OTT.S253234. eCollection 2020. Onco Targets Ther. 2020. PMID: 32606806 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources