Memory: the incomplete unhappening of differentiation
- PMID: 22035843
- DOI: 10.1016/j.immuni.2011.10.001
Memory: the incomplete unhappening of differentiation
Abstract
The signals that regulate the differentiation of central and effector memory T cells remain unclear. In this issue of Immunity, Pepper et al. (2011) and Marshall et al. (2011) implicate the differential expression of transcription factors in driving memory subtypes.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells.Immunity. 2011 Oct 28;35(4):583-95. doi: 10.1016/j.immuni.2011.09.009. Epub 2011 Oct 20. Immunity. 2011. PMID: 22018468 Free PMC article.
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Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4(+) cell properties during viral infection.Immunity. 2011 Oct 28;35(4):633-46. doi: 10.1016/j.immuni.2011.08.016. Epub 2011 Oct 20. Immunity. 2011. PMID: 22018471 Free PMC article.
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