You AhR what you eat: linking diet and immunity
- PMID: 22036556
- DOI: 10.1016/j.cell.2011.10.004
You AhR what you eat: linking diet and immunity
Abstract
The aryl hydrocarbon receptor (AhR) is responsible for the toxic effects of environmental pollutants such as dioxin, but little is known about its normal physiological functions. Li et al. (2011) now show that specific dietary compounds present in cruciferous vegetables act through the AhR to promote intestinal immune function, revealing AhR as a critical link between diet and immunity.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation.Cell. 2011 Oct 28;147(3):629-40. doi: 10.1016/j.cell.2011.09.025. Epub 2011 Oct 13. Cell. 2011. PMID: 21999944
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