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Review
. 2011 Nov;41(6):1121-32.
doi: 10.1016/j.cvsm.2011.07.005. Epub 2011 Sep 29.

Canine coronavirus: not only an enteric pathogen

Nicola Decaro  1 , Canio Buonavoglia
Affiliations
Review

Canine coronavirus: not only an enteric pathogen

Nicola Decaro et al. Vet Clin North Am Small Anim Pract. 2011 Nov.

Abstract

This article reviews the currently available literature on pantropic canine coronavirus (CCoV), providing a meaningful update on the virologic, epidemiologic, clinical, diagnostic, and prophylactic aspects of the infections caused by this emerging pathogen of dogs. It also describes pantropic CCoV-induced disease reproduced under experimental conditions.

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Figures

Fig. 1
Fig. 1
Lung of a dog with pantropic CCoV infection. Pneumonia in the caudal lobe.
Fig. 2
Fig. 2
Kidney of a dog with pantropic CCoV infection. Extensive hemorrhagic areas in the cortex.
Fig. 3
Fig. 3
Photomicrograph of the lung of a dog with pantropic CCoV infection. Densely cellular fibrinopurulent exudates, septae disruption, and diffuse edema (H&E).
Fig. 4
Fig. 4
Photomicrograph of the liver of a dog with pantropic CCoV infection. Diffuse hepatocyte degeneration and microvacuolar fatty change (H&E).
Fig. 5
Fig. 5
Photomicrograph of the kidney of a dog with pantropic CCoV infection. Coagulative necrosis associated with marked hyperemia (H&E).
Fig. 6
Fig. 6
Immunohistochemical staining with monoclonal anti-CCoV antibody of a lung section from a dog with pantropic CCoV infection. CCoV-infected cells are brown stained.
See this image and copyright information in PMC

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