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. 2011 Oct;24(4):356-8.
doi: 10.1080/08998280.2011.11928760.

Splenic hemangiomatosis

Thomas H Louis  1 , James M Sanders, Jill S Stephenson, Lori N Harbour, Kenneth L Ford 3rd
Affiliations

Splenic hemangiomatosis

Thomas H Louis et al. Proc (Bayl Univ Med Cent). 2011 Oct.
No abstract available

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Figures

Figure 1
Figure 1
Axial T2-weighted image of the lower thoracic spine shows diffuse replacement of the spleen with hyperintense lesions of various sizes (arrows).
Figure 2
Figure 2
Axial CT image of the upper abdomen shows splenomegaly with multiple hypoattenuating lesions of various sizes. These lesions contain both coarse central calcifications (arrow) as well as curvilinear peripheral calcifications (arrowhead).
Figure 3
Figure 3
Axial CT image at the level of the kidneys shows a 1-cm solid exophytic lesion arising from the anterior interpolar left kidney (arrow).
Figure 4
Figure 4
Gross photograph shows extensive replacement of the spleen by a cystic process (arrows).
Figure 5
Figure 5
Gross photograph of the spleen bisected along its long axis shows multiple cystic lesions ranging in size from 0.1 to 6 cm in diameter. Central calcifications (arrowhead) and peripheral calcifications (arrow) are present in many of these lesions.
Figure 6
Figure 6
Photomicrograph of the spleen (original magnification ×100) shows a representative cystic lesion with CD31 immunohistochemical stain, a vascular marker. The thin cellular lining (arrows) is strongly positive, consistent with vascular endothelium. The sinusoidal endothelial cells of the red pulp (arrowhead) also show strong positivity, as expected.
Figure 7
Figure 7
Photomicrograph of the spleen (original magnification ×100) shows the cystic lesions present in Figure 5 with D2-40 immunohistochemical stain, a lymphatic marker. This marker is largely negative, with sparse focal positivity in the cellular lining (arrow).
See this image and copyright information in PMC

References

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